Chronic Idiopathic Constipation

Constipation is one of the most common gastroenterologic complaints in the general population.1,2

Although traditionally regarded as less than 3 bowel movements a week, constipation is much more than a number.1 It is a bowel condition characterized by infrequent bowel movements, and/or lumpy or hard stools, and/or difficulty with defecation.

Constipation illustration

Epidemiology

Constipation is seen in 6.9% of adults in the general U.S. population,3 and becomes more common with age.2,4 Constipation is more than twice as prevalent in women,4 who are more likely than men to use laxatives and seek health care. The prevalence is higher in older individuals, and is even more common in elderly patients receiving long-term care in hospitals or nursing homes.5

Diagnosis

For a diagnosis of chronic idiopathic constipation (CIC), symptoms should be “chronic” (persisting at least six months), and “idiopathic”, lacking another known cause.2,6 Patients should experience two or more of the following symptoms:2,6,7 

  • less than 3 bowel movements per week 
  • ≥25% of bowel movements affected by lumpy or hard stools
  • ≥25% of bowel movements affected by straining
  • ≥25% of bowel movements affected by sensation of incomplete evacuation
  • ≥25% of bowel movements affected by sensation of anorectal blockage
  • ≥25% of bowel movements affected by use of manual maneuvers to facilitate defecation

Additionally, patients with CIC rarely have loose stools without use of a laxative, and have insufficient criteria for irritable bowel syndrome.2,6,7

CIC can be further divided into 3 subtypes largely based on further physiologic testing: dyssynergic defecation (outlet obstruction), slow transit constipation (STC) and normal transit constipation (NTC).7,8,9

Pathophysiology

The pathology is multi-faceted and the 3 constipation subtypes may not be mutually exclusive, with some patients experiencing two or even three of these overlapping constipation subtypes.2,7 The symptoms of dyssynergic defecation — poor coordination between rectal and abdominal wall muscles, pelvic floor muscles and anal sphincter muscles — may co-exist with the increased rectal compliance experienced with NTC.7,10 Fewer postprandial high-amplitude propagating contractions (HAPCs) are observed in both STC, characterized primarily by reduced phasic colonic motor activity, and NTC.10

Navigating CIC

A survey of patients with chronic constipation found that the most frequent symptoms were straining (79%), hard stools (71%), abdominal discomfort (62%), bloating (57%), infrequent bowel movements (57%), and feelings of incomplete evacuation after a bowel movement (54%).6 CIC patients with abdominal symptoms also report substantial missed work, and significant financial burdens.11,12 A careful history and examination of the patient experiencing constipation is essential for taking appropriate steps to manage the condition and alleviate symptoms.2

Upcoming & Past Conferences in Gastroenterology

  • Upcoming

  • Past

Digestive Disease Week (DDW), 2025

Global meeting for physicians, researchers, and industry in the fields of gastroenterology, hepatology, endoscopy, and gastrointestinal surgery.

American Society for Parenteral and Enteral Nutrition (ASPEN), 2025

March 22 - 25, 2025

Annual global conference for interdisciplinary, clinical nutrition leaders, providing the latest in clinical nutrition research, education, and products.

Annual Meeting American Academy of Allergy Asthma and Immunology (AAAAI), 2025

February 28 - March 3, 2025

Premier global educational event for allergists and immunologists, with thousands of attendees each year, discussing allergies, asthma, and immune deficiency disorders.

European Crohn's and Colitis Organisation (ECCO), 2025

February 19 - 22, 2025

Annual global congress structured around basic science, traditional medicine and clinical sessions given by some of the world's top GI specialists.

Crohn's & Colitis Congress (CCC), 2025

February 6 - 8, 2025

Annual conference for a multidisciplinary community of practitioners and researchers focusing on inflammatory bowel disease (IBD) by pairing best practices in clinical care with innovative research.

Advances in Inflammatory Bowel Diseases (AIBD), 2024

December 9 - 11, 2024

An all-encompassing event providing real-world clinical education, case studies and new evidence-based approaches in IBD management.

World Congress of Pediatric Gastroenterology, Hepatology and Nutrition (WCPGHAN), 2024

December 4 - 7, 2024

Annual forum for participants to learn about the latest advances in pediatric gastroenterology, hepatology, and nutrition, and to discuss current topics in clinical applications.

Professional Society for Health Economics and Outcomes Research (ISPOR Europe), 2024

November 17 - 20, 2024

The conference program centers on the importance of scientific evidence in understanding and improving the health and well-being of people across the globe.

North American Society For Pediatric Gastroenterology, Hepatology & Nutrition (NASPGHAN), 2024

November 6 - 9, 2024

Annual forum for participants to learn about the latest advances in pediatric gastroenterology, hepatology, and nutrition, and to discuss current topics in clinical applications.

American College of Gastroenterology (ACG), 2024

October 25 - 30, 2024

Premier event for clinicians and the general public about digestive disorders and the latest trends in GI technology and therapeutics.

American College of Allergy, Asthma & Immunology (ACAAI), 2024

October 24 - 28, 2024

Global meeting featuring thought leaders from around the world focused on advancing patient care in allergy and immunology.

Academy of Managed Care Pharmacy Nexus (AMCP Nexus), 2024

October 14 - 17, 2024

Annual event with more than 2,500 members and non-members of the AMCP to engage on the latest innovations and most intentional networking in managed care pharmacy.

American College of Clinical Pharmacy (ACCP), 2024

October 12 - 15, 2024

Annual event dedicated to excellence in clinical pharmacy practice, research, and education.

United European Gastroenterology Week (UEGW), 2024

October 12 - 15, 2024

Global congress for researchers from around the world to present their findings on gastroenterology and digestive health.

Pediatric Intestinal Failure and Rehabilitation Symposium (PIFRS), 2024

September 26 - 28, 2024

Global meeting designed to bring together international and national experts in the multidisciplinary care of the intestinal failure patient.

Gastroenterology and Hematology Advanced Practice Providers (GHAAP), 2024

September 12 - 14, 2024

Conference specifically designed by advanced practice providers (APPs) for the purpose of meeting the educational needs of APPs who specialize in the management of patients with GI disorders and chronic liver disease.

American College of Clinical Pharmacology (ACCP), 2024

September 8 - 10, 2024

Annual congress to improve global health by advancing the frontiers of

clinical pharmacology

European Society for Clinical Nutrition & Metabolism Congress (ESPEN), 2024

September 7 - 10, 2024

Annual global congress dedicated to clinical nutrition and metabolism, including basic and clinical research, education, and organization of consensus statements about clinical care.

Digestive Disease Week (DDW), 2024

May 18 - 21, 2024

Global meeting for physicians, researchers, and industry in the fields of gastroenterology, hepatology, endoscopy, and gastrointestinal surgery.

Professional Society for Health Economics and Outcomes Research (ISPOR), 2024

May 5 - 8, 2024

Leading global conference discussing how to establish, incentivize, and share value sustainable for health systems, patients, and technology developers.

Academy of Managed Care Pharmacy (AMCP), 2024

April 15 - 18, 2024

Large assembly of pharmacy and healthcare professionals dedicated to the issues of managed care pharmacy, offering immersive education sessions and keynote presentations.

Campaign Urging Research for Eosinophilic Disease (CURED), 2024

April 4 - 7, 2024

International meeting concerning the field of Eosinophilic Gastrointestinal Disorders, including EoE and other eosinophilic diseases.

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